Produção Científica - LAC

Período: 2015 a 2020. 

De La Fuente Villar, Bianca Balzano ; Neves, Elizabeth De Souza ; Louro, Virginia Clare ; Lessa, Juliana Frazão ; Rocha, Danielle Nascimento ; Gomes, Leonardo Henrique Ferreira ; Junior, Saint Clair Gomes ; Pereira, José Paulo ; Moreira, Maria Elisabeth Lopes ; Guida, Letícia Da Cunha . Toxoplasmosis in pregnancy: a clinical, diagnostic, and epidemiological study in a referral hospital in Rio de Janeiro, Brazil. Brazilian Journal of Infectious Diseases, v. 24, p. 517-523, 2020.


Costa, Régis Afonso ; Ferreira, Igor Ribeiro ; Cintra, Hiago Azevedo ; Gomes, Leonardo Henrique Ferreira ; Guida, Letícia Da Cunha . Genotype-Phenotype Relationships and Endocrine Findings in Prader-Willi Syndrome. Frontiers in Endocrinology, v. 10, p. 864, 2019.


De Oliveira Azevedo, Christianne Terra ; Do Brasil, Pedro Emmanuel A. A. ; Guida, Letícia ; Lopes Moreira, Maria Elizabeth . Performance of Polymerase Chain Reaction Analysis of the Amniotic Fluid of Pregnant Women for Diagnosis of Congenital Toxoplasmosis: A Systematic Review and Meta-Analysis. PLoS One, v. 11, p. e0149938, 2016. 


Ades AE, Brickley EB, Alexander N, Brown D, Jaenisch T, Miranda-Filho DB, Pohl M, Rosenberger KD, Soriano-Arandes A, Thorne C, Ximenes RAA, de Araújo TVB, Avelino-Silva VI, Bethencourt Castillo SE, Borja Aburto VH, Brasil P, Christie CDC, de Souza WV, Gotuzzo H JE, Hoen B, Koopmans M, Martelli CMT, Martins Teixeira M, Marques ETA, Miranda MC, Montarroyos UR, Moreira ME, Morris JG, Rockx B, Saba Villarroel PM, Soria Segarra C, Tami A, Turchi MD, Giaquinto C, de Lamballerie X, Wilder-Smith A. Zika virus infection in pregnancy: a protocol for the joint analysis of the prospective cohort studies of the ZIKAlliance, ZikaPLAN and ZIKAction consortia. BMJ Open. 2020 Dec 15;10(12):e035307. doi: 10.1136/bmjopen-2019-035307. PubMed PMID: 33323426.


Power GM, Francis SC, Sanchez Clemente N, Vasconcelos Z, Brasil P, Nielsen-Saines K, Brickley EB, Moreira ME. Examining the Association of Socioeconomic Position with Microcephaly and Delayed Childhood Neurodevelopment among Children with Prenatal Zika Virus Exposure. Viruses. 2020 Nov 23;12(11). doi: 10.3390/v12111342. PubMed PMID: 33238584; PubMed Central PMCID: PMC7700457.


Zhao Z, Shang Z, Vasconcelos Z, Li C, Jiang Y, Zu S, Zhang J, Wang F, Yao L, Jung JU, Brasil P, Moreira ME, Qin CF, Kerin T, Nielsen-Saines K, Cheng G, Zhang X, Xu Z. Zika Virus Infection Leads to Variable Defects in Multiple Neurological Functions and Behaviors in Mice and Children. Adv Sci (Weinh). 2020 Sep;7(18):1901996. doi: 10.1002/advs.201901996. eCollection 2020 Sep. PubMed PMID: 32999822; PubMed Central PMCID: PMC7509663.


Brasil P, Vasconcelos Z, Kerin T, Gabaglia CR, Ribeiro IP, Bonaldo MC, Damasceno L, Pone MV, Pone S, Zin A, Tsui I, Adachi K, Pereira JP Jr, Gaw SL, Carvalho L, Cunha DC, Guida L, Rocha M, Cherry JD, Wang L, Aliyari S, Cheng G, Foo SS, Chen W, Jung J, Brickley E, Moreira MEL, Nielsen-Saines K. Zika virus vertical transmission in children with confirmed antenatal exposure. Nat Commun. 2020 Jul 14;11(1):3510. doi: 10.1038/s41467-020-17331-0. PubMed PMID: 32665616; PubMed Central PMCID: PMC7360785.


Cranston JS, Tiene SF, Nielsen-Saines K, Vasconcelos Z, Pone MV, Pone S, Zin A, Salles TS, Pereira JP Jr, Orofino D, Brasil P, Kerin T, Adachi K, Soares FM, Dunshee de Abranches A, da Costa ACC, Lopes Moreira ME. Association Between Antenatal Exposure to Zika Virus and Anatomical and Neurodevelopmental Abnormalities in Children. JAMA Netw Open. 2020 Jul 1;3(7):e209303. doi: 10.1001/jamanetworkopen.2020.9303. PubMed PMID: 32633763; PubMed Central PMCID: PMC7341180.


Adachi K, Romero T, Nielsen-Saines K, Pone S, Aibe M, Barroso de Aguiar E, Sim M, Brasil P, Zin A, Tsui I, Gaw SL, Halai UA, Vasconcelos Z, Pereira JP, Salles TS, Barbosa CN, Portari E, Cherry JD, Pone M, Moreira ME. Early Clinical Infancy Outcomes for Microcephaly and/or Small for Gestational Age Zika-Exposed Infants. Clin Infect Dis. 2020 Jun 10;70(12):2663-2672. doi: 10.1093/cid/ciz704. PubMed PMID: 31346616; PubMed Central PMCID: PMC7286378.


Aguiar RS, Pohl F, Morais GL, Nogueira FCS, Carvalho JB, Guida L, Arge LWP, Melo A, Moreira MEL, Cunha DP, Gomes L, Portari EA, Velasquez E, Melani RD, Pezzuto P, de Castro FL, Geddes VEV, Gerber AL, Azevedo GS, Schamber-Reis BL, Gonçalves AL, Junqueira-de-Azevedo I, Nishiyama MY Jr, Ho PL, Schanoski AS, Schuch V, Tanuri A, Chimelli L, Vasconcelos ZFM, Domont GB, Vasconcelos ATR, Nakaya HI. Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome. Sci Signal. 2020 Jun 9;13(635). doi: 10.1126/scisignal.aay6736. PubMed PMID: 32518143.


Silva-Freitas ML, Corrêa-Castro G, Cota GF, Giacoia-Gripp C, Rabello A, Teixeira Dutra J, de Vasconcelos ZFM, Savino W, Da-Cruz AM, Santos-Oliveira JR. Impaired Thymic Output Can Be Related to the Low Immune Reconstitution and T Cell Repertoire Disturbances in Relapsing Visceral Leishmaniasis Associated HIV/AIDS Patients. Front Immunol. 2020;11:953. doi: 10.3389/fimmu.2020.00953. eCollection 2020. PubMed PMID: 32508833; PubMed Central PMCID: PMC7251171.


Sobhani NC, Avvad-Portari E, Nascimento ACM, Machado HN, Lobato DSS, Pereira JP, Esquivel MS, Vasconcelos ZC, Zin AA, Tsui I, Adachi K, Brickley EB, Fisher SJ, Nielsen-Saines K, Brasil P, Moreira ME, Gaw SL. Discordant Zika Virus Findings in Twin Pregnancies Complicated by Antenatal Zika Virus Exposure: A Prospective Cohort. J Infect Dis. 2020 May 11;221(11):1838-1845. doi: 10.1093/infdis/jiz629. PubMed PMID: 31773163; PubMed Central PMCID: PMC7213575.


Peçanha PM, Gomes Junior SC, Pone SM, Pone MVDS, Vasconcelos Z, Zin A, Vilibor RHH, Costa RP, Meio MDBB, Nielsen-Saines K, Brasil P, Brickley E, Lopes Moreira ME. Neurodevelopment of children exposed intra-uterus by Zika virus: A case series. PLoS One. 2020;15(2):e0229434. doi: 10.1371/journal.pone.0229434. eCollection 2020. PubMed PMID: 32109947; PubMed Central PMCID: PMC7048286.


Messias CV, Loss-Morais G, Carvalho JB, González MN, Cunha DP, Vasconcelos Z, Arge LWP, Farias-de-Oliveira DA, Gerber AL, Portari EA, Ferreira N, Raphael LMS, Bonaldo MC, Riederer I, Lopes Moreira ME, Cotta-de-Almeida V, Vasconcelos ATR, Mendes-da-Cruz DA, Savino W. Zika virus targets the human thymic epithelium. Sci Rep. 2020 Jan 28;10(1):1378. doi: 10.1038/s41598-020-58135-y. PubMed PMID: 31992777; PubMed Central PMCID: PMC6987159.


Messias CV, Lemos JP, Cunha DP, Vasconcelos Z, Raphael LMS, Bonaldo MC, Cister-Alves B, Bou-Habib DC, Cotta-de-Almeida V, Savino W, Mendes-da-Cruz DA. Zika virus infects human blood mononuclear cells. BMC Infect Dis. 2019 Nov 21;19(1):986. doi: 10.1186/s12879-019-4622-y. PubMed PMID: 31752731; PubMed Central PMCID: PMC6873492.


Nielsen-Saines K, Brasil P, Kerin T, Vasconcelos Z, Gabaglia CR, Moreira ME. Reply to 'A critical analysis of neurodevelopmental and neurosensory outcomes after 2 years for children with in utero Zika virus exposure'. Nat Med. 2019 Nov;25(11):1642-1643. doi: 10.1038/s41591-019-0631-z. PubMed PMID: 31649351; PubMed Central PMCID: PMC7261141.


Cirne-Santos CC, Barros CS, Nogueira CCR, Azevedo RC, Yamamoto KA, Meira GLS, de Vasconcelos ZFM, Ratcliffe NA, Teixeira VL, Schmidt-Chanasit J, Ferreira DF, Paixão ICNP. Inhibition by Marine Algae of Chikungunya Virus Isolated From Patients in a Recent Disease Outbreak in Rio de Janeiro. Front Microbiol. 2019;10:2426. doi: 10.3389/fmicb.2019.02426. eCollection 2019. PubMed PMID: 31708898; PubMed Central PMCID: PMC6821653.


Pereira JP, Maykin MM, Vasconcelos Z, Avvad-Portari E, Zin AA, Tsui I, Brasil P, Nielsen-Saines K, Moreira ME, Gaw SL. The Role of Amniocentesis in the Diagnosis of Congenital Zika Syndrome. Clin Infect Dis. 2019 Aug 1;69(4):713-716. doi: 10.1093/cid/ciz013. PubMed PMID: 30624579; PubMed Central PMCID: PMC6669287.


Nielsen-Saines K, Brasil P, Kerin T, Vasconcelos Z, Gabaglia CR, Damasceno L, Pone M, Abreu de Carvalho LM, Pone SM, Zin AA, Tsui I, Salles TRS, da Cunha DC, Costa RP, Malacarne J, Reis AB, Hasue RH, Aizawa CYP, Genovesi FF, Einspieler C, Marschik PB, Pereira JP, Gaw SL, Adachi K, Cherry JD, Xu Z, Cheng G, Moreira ME. Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children. Nat Med. 2019 Aug;25(8):1213-1217. doi: 10.1038/s41591-019-0496-1. Epub 2019 Jul 8. PubMed PMID: 31285631; PubMed Central PMCID: PMC6689256.


Pool KL, Adachi K, Karnezis S, Salamon N, Romero T, Nielsen-Saines K, Pone S, Boechat M, Aibe M, Gomes da Silva T, Ribeiro CTM, Boechat MI, Brasil P, Zin A, Tsui I, Gaw SL, Daltro P, Ribeiro BG, Fazecas T, Hygino da Cruz LC, Nogueira R, Vasconcelos Z, Pereira JP Jr, Saad Salles T, Barbosa CN, Chen W, Foo SS, Jung J, Moreira ME, Pone M. Association Between Neonatal Neuroimaging and Clinical Outcomes in Zika-Exposed Infants From Rio de Janeiro, Brazil. JAMA Netw Open. 2019 Jul 3;2(7):e198124. doi: 10.1001/jamanetworkopen.2019.8124. PubMed PMID: 31365112; PubMed Central PMCID: PMC6669783.


Cheminant M, Mahlaoui N, Desconclois C, Canioni D, Ysebaert L, Dupré L, Vasconcelos Z, Malphettes M, Moshous D, Neven B, Rohrlich PS, Bernard M, Bertrand Y, Fischer A, Suarez F. Lymphoproliferative disease in patients with Wiskott-Aldrich syndrome: Analysis of the French Registry of Primary Immunodeficiencies. J Allergy Clin Immunol. 2019 Jun;143(6):2311-2315.e7. doi: 10.1016/j.jaci.2019.01.046. Epub 2019 Feb 20. PubMed PMID: 30796981.


Ribeiro Ferreira I, Darleans Dos Santos Cunha W, Henrique Ferreira Gomes L, Azevedo Cintra H, Lopes Cabral Guimarães Fonseca L, Ferreira Bastos E, Clinton Llerena J Jr, Farias Meira de Vasconcelos Z, da Cunha Guida L. A rapid and accurate methylation-sensitive high-resolution melting analysis assay for the diagnosis of Prader Willi and Angelman patients. Mol Genet Genomic Med. 2019 Jun;7(6):e637. doi: 10.1002/mgg3.637. Epub 2019 Apr 29. PubMed PMID: 31033246; PubMed Central PMCID: PMC6565559.


Castro FL, Geddes VEV, Monteiro FLL, Gonçalves RMDT, Campanati L, Pezzuto P, Paquin-Proulx D, Schamber-Reis BL, Azevedo GS, Gonçalves AL, Cunha DP, Moreira MEL, Vasconcelos ZFM, Chimeli L, Melo A, Tanuri A, Nixon DF, Ribeiro-Alves M, Aguiar RS.

MicroRNAs 145 and 148a Are Upregulated During Congenital Zika Virus Infection. ASN Neuro. 2019 Jan-Dec;11:1759091419850983. doi: 10.1177/1759091419850983. PubMed PMID: 31213064; PubMed Central PMCID: PMC6585135.


Lopes Moreira ME, Nielsen-Saines K, Brasil P, Kerin T, Damasceno L, Pone M, Carvalho LMA, Pone SM, Vasconcelos Z, Ribeiro IP, Zin AA, Tsui I, Adachi K, Gaw SL, Halai UA, Salles TS, da Cunha DC, Bonaldo MC, Raja Gabaglia C, Guida L, Malacarne J, Costa RP, Gomes SC Jr, Reis AB, Soares FVM, Hasue RH, Aizawa CYP, Genovesi FF, Aibe M, Einspieler C, Marschik PB, Pereira JP Jr, Portari EA, Janzen C, Cherry JD. Neurodevelopment in Infants Exposed to Zika Virus In Utero. N Engl J Med. 2018 Dec 13;379(24):2377-2379. doi: 10.1056/NEJMc1800098. PubMed PMID: 30575464; PubMed Central PMCID: PMC6478167.


Pereira JP Jr, Nielsen-Saines K, Sperling J, Maykin MM, Damasceno L, Cardozo RF, Valle HA, Dutra BRT, Gama HD, Adachi K, Zin AA, Tsui I, Vasconcelos Z, Brasil P, Moreira ME, Gaw SL. Association of Prenatal Ultrasonographic Findings With Adverse Neonatal Outcomes Among Pregnant Women With Zika Virus Infection in Brazil. JAMA Netw Open. 2018 Dec 7;1(8):e186529. doi: 10.1001/jamanetworkopen.2018.6529. PubMed PMID: 30646333; PubMed Central PMCID: PMC6324324.


Zin AA, Tsui I, Rossetto JD, Gaw SL, Neves LM, Zin OA, Haefeli L, Barros Silveira Filho JC, Adachi K, Vinicius da Silva Pone M, Pone SM, Molleri N, Pereira JP Jr, Belfort R, Arumugaswami V, Vasconcelos Z, Brasil P, Nielsen-Saines K, Lopes Moreira ME.

Visual function in infants with antenatal Zika virus exposure. J AAPOS. 2018 Dec;22(6):452-456.e1. doi: 10.1016/j.jaapos.2018.07.352. Epub 2018 Oct 22. PubMed PMID: 30359768; PubMed Central PMCID: PMC6289819.


Tsui I, Moreira MEL, Rossetto JD, Vasconcelos Z, Gaw SL, Neves LM, Zin OA, Haefeli L, Silveira Filho JCB, Gomes SC Jr, Adachi K, Pone MVDS, Pone SM, Pereira JP Jr, Belfort R, Arumugaswami V, Brasil P, Nielsen-Saines K, Zin AA. Eye Findings in Infants With Suspected or Confirmed Antenatal Zika Virus Exposure. Pediatrics. 2018 Oct;142(4). doi: 10.1542/peds.2018-1104. Epub 2018 Sep 13. PubMed PMID: 30213843; PubMed Central PMCID: PMC6317824.


Costa APE, Saad T, Ignez LS, Gamarano G, Lazzari AP, Vasconcelos Z. Pediatric Multiple Sclerosis: The role of magnetic resonance imaging and chemokine profile in the diagnosis and follow-up. Rev Assoc Med Bras (1992). 2018 Aug;64(8):672-675. doi: 10.1590/1806-9282.64.08.672. PubMed PMID: 30673035.


Nico D, Conde L, Rivera-Correa JL, Vasconcelos-Dos-Santos A, Mesentier-Louro L, Freire-de-Lima L, Arruda MB, Freire-de-Lima CG, Ferreira ODC Jr, Lopes Moreira ME, Zin AA, Vasconcelos ZFM, Otero RM, Palatnik-de-Sousa CB, Tanuri A, Todeschini AR, Savino W, Rodriguez A, Morrot A. Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection. Front Med (Lausanne). 2018;5:25. doi: 10.3389/fmed.2018.00025. eCollection 2018. PubMed PMID: 29594116; PubMed Central PMCID: PMC5854646.


Chimelli L, Moura Pone S, Avvad-Portari E, Farias Meira Vasconcelos Z, Araújo Zin A, Prado Cunha D, Raposo Thompson N, Lopes Moreira ME, Wiley CA, da Silva Pone MV. Persistence of Zika Virus After Birth: Clinical, Virological, Neuroimaging, and Neuropathological Documentation in a 5-Month Infant With Congenital Zika Syndrome. J Neuropathol Exp Neurol. 2018 Mar 1;77(3):193-198. doi: 10.1093/jnen/nlx116. PubMed PMID: 29346650.


Houmadi R, Guipouy D, Rey-Barroso J, Vasconcelos Z, Cornet J, Manghi M, Destainville N, Valitutti S, Allart S, Dupré L. The Wiskott-Aldrich Syndrome Protein Contributes to the Assembly of the LFA-1 Nanocluster Belt at the Lytic Synapse. Cell Rep. 2018 Jan 23;22(4):979-991. doi: 10.1016/j.celrep.2017.12.088. Epub 2018 Jan 28. PubMed PMID: 29386139.


de Vasconcelos ZFM, Azevedo RC, Thompson N, Gomes L, Guida L, Moreira MEL. Challenges for molecular and serological ZIKV infection confirmation. Childs Nerv Syst. 2018 Jan;34(1):79-84. doi: 10.1007/s00381-017-3641-5. Epub 2017 Nov 6. Review. PubMed PMID: 29110196.


Zin AA, Tsui I, Rossetto J, Vasconcelos Z, Adachi K, Valderramos S, Halai UA, Pone MVDS, Pone SM, Silveira Filho JCB, Aibe MS, da Costa ACC, Zin OA, Belfort R Jr, Brasil P, Nielsen-Saines K, Moreira MEL. Screening Criteria for Ophthalmic Manifestations of Congenital Zika Virus Infection. JAMA Pediatr. 2017 Sep 1;171(9):847-854. doi: 10.1001/jamapediatrics.2017.1474. PubMed PMID: 28715527; PubMed Central PMCID: PMC5710409.


Chicaybam L, Barcelos C, Peixoto B, Carneiro M, Limia CG, Redondo P, Lira C, Paraguassú-Braga F, Vasconcelos ZF, Barros L, Bonamino MH. An Efficient Electroporation Protocol for the Genetic Modification of Mammalian Cells. Front Bioeng Biotechnol.

2016;4:99. doi: 10.3389/fbioe.2016.00099. eCollection 2016. PubMed PMID: 28168187; PubMed Central PMCID: PMC5253374.
Medeiros Sde O, Abreu CM, Delvecchio R, Ribeiro AP, Vasconcelos Z, Brindeiro Rde M, Tanuri A. Follow-up on long-term antiretroviral therapy for cats infected with feline immunodeficiency virus. J Feline Med Surg. 2016 Apr;18(4):264-72. doi: 10.1177/1098612X15580144. Epub 2015 Apr 8. PubMed PMID: 25855689.


Vasconcelos Z, Müller S, Guipouy D, Yu W, Christophe C, Gadat S, Valitutti S, Dupré L. Individual Human Cytotoxic T Lymphocytes Exhibit Intraclonal Heterogeneity during Sustained Killing. Cell Rep. 2015 Jun 9;11(9):1474-85. doi: 10.1016/j.celrep.2015.05.002. Epub 2015 May 28. PubMed PMID: 26027932.


Cotta-de-Almeida V, Dupré L, Guipouy D, Vasconcelos Z. Signal Integration during T Lymphocyte Activation and Function: Lessons from the Wiskott-Aldrich Syndrome. Front Immunol. 2015;6:47. doi: 10.3389/fimmu.2015.00047. eCollection 2015. Review. PubMed PMID: 25709608; PubMed Central PMCID: PMC4321635.